Ohio's premier science and industry museum was designed by Japanese-born architect Arata Isozaki. Located on the Scioto River, the structure cleverly incorporates a 1924 Beaux-Arts high school and encompasses 320,000sq ft of space. Nestled within are a giant "extreme screen" theater, a planetarium, a motion simulator and ten state-of-the-art "Learning Worlds." Using video, hands-on experimentation, computers, artifacts and live theater, these are among the most advanced science exhibits you'll find.